p

740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-terminal SH2 structural domains of p85, but not to GST alone.

[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM).

740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.

740 Y-P(TFA) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.

P-113 acetate is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5, shows good safety and efficacy profiles in gingivitis and human immunodeficiency virus (HIV) patients with oral candidiasis.

[D-Trp7,9,10]-Substance P acetate is an analogue of substance P which inhibits ion conductance through nicotinic acetylcholine receptors.

P-113 is a peptide with antimicrobial activity.

N-(p-Tosyl)-GPR-pNA acetate is a colorimetric substrate for thrombin that can act as a measure of thrombin activity.

Biotin-Substance P acts as a neurotransmitter and neuromodulator in the central nervous system. Neurokinin 1 receptor (NK1R) is the endogenous receptor of Biotin-Substance P.

[Tyr(P)4] Angiotensin II is a peptide that affects vascular smooth muscle by causing contraction in normal arteries and inducing hypertrophy or hyperplasia in cultured cells or diseased vessels.

L-Leucine benzyl ester p-toluenesulfonate salt (Catalog No. T65805, CAS No. 1738-77-8) is a valuable organic compound for life sciences research.

2-Amino-2-(p-tolyl)acetic acid is a valuable organic compound for life sciences research (catalog number: T66688, CAS number: 13227-01-5).

Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects

Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .

Substance P(1-7) TFA is a fragment of neuropeptide P (SP) with anti-nociceptive activity. It prevents morphine-induced spontaneous pain behavior through the spinal NMDA-NO cascade, and can be used in research on neurological diseases.

[Pro9]-Substance P is a highly effective, reversible, and selective NK-1 tachykinin receptor agonist with an EC50 value of 0.93 nM [1].

(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist and effectively inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats [1].

[Glp6] Substance P (6-11) is an analogue of the native peptide Substance P (6-11), acting on 'septide-sensitive' tachykinin receptors and stimulating the formation of [3H]-inositol monophosphate ([3H]-IP1) in rat urinary bladder, as evidenced by references [1] [2].

[Glp5] Substance P (5-11), an octapeptide, is a key fragment of substance P in the rat central nervous system (CNS) and plays a localized role in modulating dopamine release in the rat striatum [1].

[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is an analogue of Substance P that acts on the neurokinin 1 receptor (NK1R) in rat brain, similarly to Substance P but with a significantly extended duration of action. This compound selectively enhances dopamine metabolism within the mesencephalon and midbrain cortex, increases motor activity, and facilitates the resumption of addictive agent-seeking behavior in rats [1] [2] [3].

[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with inhibitory affinities (K_i values) of 1 μM for NK-1, 1.3 μM for NK-2, and approximately 9 μM for NK-3 receptors [1].

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing their effects [1].

[D-Pro2,D-Trp7,9] Substance P, an analogue of Substance P, acts as both a weak agonist and a potent, specific, competitive antagonist to Substance P [1] [2].

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P antagonist [1].