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Scabertopin

Name: Scabertopin
Brand: TargetMol
SKU: TQ0096
Price: 81 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TQ0096 Copy Product Info

Purity: 99.13%

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Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities.

Cas No. 185213-52-9

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Pack Size	Price	USA Stock	Global Stock
1 mg	$81	-	In Stock
5 mg	$213	-	In Stock
10 mg	$318	-	In Stock
25 mg	$533	-	In Stock
50 mg	$759	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.13%

Appearance:Solid

Color:White

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COA HPLC HNMR

Product Introduction

Bioactivity

Description

Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities.

Chemical Properties

Molecular Weight	358.39
Formula	C₂₀H₂₂O₆
Cas No.	185213-52-9
Smiles	[H][C@]12C\C(C)=C/[C@@]3([H])OC(=O)C(=C)[C@]3([H])[C@H](CC(=C1)C(=O)O2)OC(=O)C(\C)=C/C
Relative Density.	1.24 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Keep away from direct sunlight,Keep away from moisture,Store at low temperature,The compound is unstable in solution. Please use soon Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (418.54 mM), Sonication is recommended. (The compound is unstable in solution, please use soon.)

In Vivo Formulation

10% DMSO+90% Saline: < 10 mg/mL (27.9 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

10% DMSO+90% Corn oil: 10 mg/mL (27.9 mM), Solution.

10% DMSO+90% (20% SBE-β-CD in Saline): < 10 mg/mL (27.9 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

10% DMSO+40% PEG300+5% Tween 80+45% Saline: < 10 mg/mL (27.9 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7903 mL	13.9513 mL	27.9026 mL	139.5128 mL
5 mM	0.5581 mL	2.7903 mL	5.5805 mL	27.9026 mL
10 mM	0.2790 mL	1.3951 mL	2.7903 mL	13.9513 mL
20 mM	0.1395 mL	0.6976 mL	1.3951 mL	6.9756 mL
50 mM	0.0558 mL	0.2790 mL	0.5581 mL	2.7903 mL
100 mM	0.0279 mL	0.1395 mL	0.2790 mL	1.3951 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc