ARNT Protein, Human, Recombinant (His)

Catalog No. TMPH-00957 Copy Product Info

ARNT Protein, Human, Recombinant (His) is expressed in Yeast.

ARNT Protein, Human, Recombinant (His)

Catalog No. TMPH-00957

Copy Product Info

ARNT Protein, Human, Recombinant (His) is expressed in Yeast.

Pack Size	Price	USA Stock	Global Stock
5 μg	$86	20 days	20 days
10 μg	$138	20 days	20 days
20 μg	$231	20 days	20 days
50 μg	$348	20 days	20 days
100 μg	$480	20 days	20 days
200 μg	$743	20 days	20 days
500 μg	$1,330	20 days	20 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
Species	Human
Expression System	P. pastoris (Yeast)
Tag	N-6xHis
Accession Number	P27540
Synonyms	Hypoxia-inducible factor 1-beta (HIF-1-beta;HIF1-beta),Dioxin receptor, nuclear translocator,Class E basic helix-loop-helix protein 2 (bHLHe2),BHLHE2,Aryl hydrocarbon receptor nuclear translocator,ARNT protein,ARNT
Amino Acid	MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNQEWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPT
Construction	1-474 aa
Protein Purity	> 90% as determined by SDS-PAGE.
Molecular Weight	54.8 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Tris-based buffer, 50% glycerol
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.