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ARNT Protein, Human, Recombinant (His)

Catalog No. TMPH-00957
Synonyms: Hypoxia-inducible factor 1-beta, Class E basic helix-loop-helix protein 2, HIF-1-beta, Aryl hydrocarbon receptor nuclear translocator, HIF1-beta, BHLHE2, ARNT protein

ARNT Protein, Human, Recombinant (His) is expressed in Yeast.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
ARNT Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 231.00
100 μg 20 days $ 437.00
500 μg 20 days $ 1,210.00
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Biological Description
Technical Params
Product Properties
Description ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
Species Human
Expression System Yeast
Tag N-terminal 6xHis-tagged
Accession Number P27540
Synonyms Hypoxia-inducible factor 1-beta, Class E basic helix-loop-helix protein 2, HIF-1-beta, Aryl hydrocarbon receptor nuclear translocator, HIF1-beta, BHLHE2, ARNT protein
Amino Acid MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNQEWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPT Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 1-474 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 54.8 kDa as predicted
Formulation Tris-based buffer,50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.

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Keywords

ARNT Protein, Human, Recombinant (His) Hypoxia-inducible factor 1-beta Class E basic helix-loop-helix protein 2 HIF-1-beta Aryl hydrocarbon receptor nuclear translocator HIF1-beta BHLHE2 ARNT protein recombinant recombinant-proteins proteins protein

 

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