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Anti-VAPB Antibody (1M998)

😃Good
Catalog No. TMAY-01128
Alias VAP-B, VAMP-B, VAMP (vesicle-associated membrane protein)-associated protein B and C, ALS8

Anti-VAPB Antibody (1M998) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (1M998) can be used in IHC-P.

Anti-VAPB Antibody (1M998)

Anti-VAPB Antibody (1M998)

😃Good
Catalog No. TMAY-01128Alias VAP-B, VAMP-B, VAMP (vesicle-associated membrane protein)-associated protein B and C, ALS8
Anti-VAPB Antibody (1M998) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (1M998) can be used in IHC-P.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: IHC-P

Reactivity: Human
AliasVAP-B, VAMP-B, VAMP (vesicle-associated membrane protein)-associated protein B and C, ALS8
Ig Type
Rabbit IgG
Clone
1M998
Reactivity
Human
Verified Activity
1. Immunochemical staining of human VAPB in human pancreas with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human VAPB in human liver with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
3. Immunochemical staining of human VAPB in human cirrhosis with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
4. Immunochemical staining of human VAPB in human brain with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human VAPB / VAP-B (rh VAPB / VAP-B; TMPY-02196; O95292-1; Met1-Pro132).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundVesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated protein (VAP) family. VAPB contains one MSP domain. VAPB may play a role in vesicle trafficking. VAPB forms a heterodimer with VAPA. VAPB interacts with VAMP1 and VAMP2. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 ( ALS8 ) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Defects in VAPB are also a cause of spinal muscular atrophy autosomal dominant Finkel type (SMAF) which is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human VAPB/VAP-B Protein (TMPY-02196)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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