IGF2/IGF-II Protein, Human, Recombinant (hFc)

Name: IGF2/IGF-II Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00061
Rating: 4.5 (1 reviews)

(Synonyms: Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2) Copy Product Info

Synonyms: Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2

Catalog No. TMPK-00061 Copy Product Info

The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.

IGF2/IGF-II Protein, Human, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$65	7-10 days	7-10 days
10 µg	$103	7-10 days	7-10 days
20 µg	$165	7-10 days	7-10 days
50 µg	$297	7-10 days	7-10 days
100 µg	$474	-	In Stock
200 µg	$757	7-10 days	7-10 days
500 µg	$1,360	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human IGFBP-3, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IGF II, hFc Tag with the EC50 of 0.19μg/ml determined by ELISA.
Description	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	P01344-1
Construction	Ala25-Glu91
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
Research Background	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.

Chemical Properties

Molecular Weight

33.00 kDa (predicted). Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.