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Anti-Carbonic Anhydrase 9 Antibody (7K666)
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Catalog No. TMAY-03392
Alias MN, Carbonic Anhydrase IX, CAIX
Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.
Anti-Carbonic Anhydrase 9 Antibody (7K666)
Anti-Carbonic Anhydrase 9 Antibody (7K666)
😃Good
Catalog No. TMAY-03392Alias MN, Carbonic Anhydrase IX, CAIX
Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Mouse |
| Alias | MN, Carbonic Anhydrase IX, CAIX |
| Ig Type | Rabbit IgG |
| Clone | 7K666 |
| Reactivity | Mouse |
| Verified Activity | Immunochemical staining of mouse CAR9 in mouse stomach (from 2 donors) with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:250-1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase IX / CAR9 (rM Carbonic Anhydrase IX / CAR9; TMPY-01700; NP_647466.2; Met1-Asp390). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse Carbonic Anhydrase IX / CAR9 protein (TMPY-01700) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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