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Anti-Carbonic Anhydrase 9 Antibody (7K666)

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Catalog No. TMAY-03392

Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.

Anti-Carbonic Anhydrase 9 Antibody (7K666)

Anti-Carbonic Anhydrase 9 Antibody (7K666)

😃Good
Catalog No. TMAY-03392
Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.
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100 μL255 € 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
Clone
7K666
Reactivity
Mouse
Verified Activity
Immunochemical staining of mouse CAR9 in mouse stomach (from 2 donors) with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:250-1:1000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase IX / CAR9 (rM Carbonic Anhydrase IX / CAR9; TMPY-01700; NP_647466.2; Met1-Asp390).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Carbonic Anhydrase IX / CAR9 protein (TMPY-01700)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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