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CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Catalog No. TMPH-03017
Synonyms: Cytochrome P450-14DM, Sterol 14alpha-demethylase, Sterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-LIA1, cyp51

Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.

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CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 491.00
100 μg 20 days $ 1,370.00
1 mg 20 days $ 2,750.00
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Biological Description
Technical Params
Product Properties
Description Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
Species Mycobacterium tuberculosis
Expression System Baculovirus
Tag N-terminal 10xHis-tagged and C-terminal Myc-tagged
Accession Number P9WPP8
Synonyms Cytochrome P450-14DM, Sterol 14alpha-demethylase, Sterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-LIA1, cyp51
Amino Acid MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLHNAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVLIAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPACVRYRRRTGV Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 1-451 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 54.8 kDa as predicted
Formulation Tris-based buffer,50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.

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Keywords

CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Cytochrome P450-14DM Sterol 14alpha-demethylase Sterol 14-alpha demethylase CYPLI Cytochrome P450 51 Cytochrome P450-LIA1 cyp51 recombinant recombinant-proteins proteins protein

 

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