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Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM.
Description | Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 5D841 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 (rh CD85 / ILT2 / ILR1; TMPY-03995; ADJ55949.1; Met1-His458) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
Conjucates | PE |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human CD85 / ILT2 / ILR1 protein (TMPY-03995) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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