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Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

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Catalog No. TMAY-02808P

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM.

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841)

🥰Excellent
Catalog No. TMAY-02808P
Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) is a PE-conjugated Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody-PE (5D841) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
5D841
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 (rh CD85 / ILT2 / ILR1; TMPY-03995; ADJ55949.1; Met1-His458) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundLILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human CD85 / ILT2 / ILR1 protein (TMPY-03995)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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