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Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody
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Catalog No. TMAC-02510
Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDM2 (Ser166). Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody can be used in WB,IHC,IF.
Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody
Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody
😃Good
Catalog No. TMAC-02510
Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDM2 (Ser166). Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody can be used in WB,IHC,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDM2 (Ser166). Anti-Phospho-MDM2 (Ser166) Polyclonal Antibody can be used in WB,IHC,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 166 (A-I-S(p)-E-T) derived from Human MDM2 |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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