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LDHA Protein, Human, Recombinant (His)

Catalog No. TMPJ-00724
Synonyms: LDH-M, Renal Carcinoma Antigen NY-REN-59, Cell Proliferation-Inducing Gene 19 Protein, LDH Muscle Subunit, LDHA, LDH-A, L-Lactate Dehydrogenase A Chain

L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
LDHA Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
Species Human
Expression System E. coli
Tag N-6His
Accession Number P00338
Synonyms LDH-M, Renal Carcinoma Antigen NY-REN-59, Cell Proliferation-Inducing Gene 19 Protein, LDH Muscle Subunit, LDHA, LDH-A, L-Lactate Dehydrogenase A Chain
Amino Acid Met1-Phe332
Construction Recombinant Human L-Lactate Dehydrogenase A Chain is produced by our E.coli expression system and the target gene encoding Met1-Phe332 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 37 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, 1mM EDTA, 50% Glycerol, pH8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.

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Keywords

LDHA Protein, Human, Recombinant (His) LDH-M Renal Carcinoma Antigen NY-REN-59 Cell Proliferation-Inducing Gene 19 Protein LDH Muscle Subunit LDHA LDH-A L-Lactate Dehydrogenase A Chain recombinant recombinant-proteins proteins protein

 

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