TPSB2 Protein, Human, Recombinant (His)

Name: TPSB2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00542
Rating: 4.5 (1 reviews)

(Synonyms: Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2) Copy Product Info

Synonyms: Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2

Catalog No. TMPJ-00542 Copy Product Info

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 99.9%

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Loaded Anti-Human Tryptase mAb-Fc on AHC Biosensor, can bind Human TPSB2-His with an affinity constant of <10^-3 nM as determined in BLI assay (Regularly tested)
Description	Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	AAH29356.1
Amino Acid	Ala19-Pro275
Construction	Ala19-Pro275
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Synonyms	Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2
Research Background	Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

Chemical Properties

Molecular Weight

30-35 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.