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Anti-IGFBP-4 Antibody (2F108)
😃Good
Catalog No. TMAY-01381
Alias insulin-like growth factor binding protein 4
Anti-IGFBP-4 Antibody (2F108) is a Mouse antibody targeting IGFBP-4. Anti-IGFBP-4 Antibody (2F108) can be used in ELISA.
Anti-IGFBP-4 Antibody (2F108)
Anti-IGFBP-4 Antibody (2F108)
😃Good
Catalog No. TMAY-01381Alias insulin-like growth factor binding protein 4
Anti-IGFBP-4 Antibody (2F108) is a Mouse antibody targeting IGFBP-4. Anti-IGFBP-4 Antibody (2F108) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IGFBP-4 Antibody (2F108) is a Mouse antibody targeting IGFBP-4. Anti-IGFBP-4 Antibody (2F108) can be used in ELISA. |
| Synonyms | insulin-like growth factor binding protein 4 |
| Ig Type | Mouse IgG1 |
| Clone | 2F108 |
| Reactivity | Human |
| Specificity | Human IGFBP4 No cross-reactivity in ELISA with Human IGFBP3 / IBP3 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IGFBP4 (rh IGFBP4; TMPY-00836; NP_001543.2; Met 1-Glu 258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Insulin-like growth factor-binding protein 4 (IGFBP-4) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGF-binding protein-4 (IGFBP-4) inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. Expression of IGFBP-4 mRNA in nontransgenic littermates was maximal in the liver and kidney. IGFBP-4 is a functional antagonist of IGF-I action on SMC. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IGFBP4 protein (TMPY-00836) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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