Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies..
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 313.00 | |
500 μg | 5 days | $ 1,260.00 | |
1 mg | 5 days | $ 2,090.00 |
Description | Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies.. |
Species | Human |
Expression System | HEK293 Cells |
Tag | N-His-Avi |
Accession Number | O15123-1 |
Synonyms | angiopoietin 2, angiopoietin-2a, angiopoitin 2, ANG-2, Tie2-ligand, angiopoietin-2B, ANGPT2, AGPT2, ANG2, Angiopoietin-2 |
Construction | Lys275-Phe496 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 28.4 kDa (predicted). Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies.. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi) angiopoietin 2 ANG 2 AGPT 2 ANGPT 2 angiopoietin-2a angiopoitin 2 ANG-2 Tie2-ligand angiopoietin-2B ANGPT2 ANGPT-2 AGPT-2 AGPT2 ANG2 Angiopoietin-2 recombinant recombinant-proteins proteins protein