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PDIA3 Protein, Human, Recombinant (His)
(Synonyms: Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein) Copy Product InfoSynonyms: Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein
Catalog No. TMPJ-00935 Copy Product Info
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | - | In Stock | |
| 10 μg | $183 | - | In Stock | |
| 20 μg | $292 | - | In Stock | |
| 50 μg | $545 | - | In Stock | |
| 100 μg | $813 | - | In Stock | |
| 200 μg | $1,190 | 7-10 days | 7-10 days | |
| 500 μg | $2,070 | - | In Stock | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | P30101 |
| Amino Acid | Ser25-Leu505 |
| Construction | Ser25-Leu505 |
| Protein Purity | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 7.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein |
| Research Background |
| Molecular Weight | 60 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: PDIA3 Protein, Human, Recombinant (His) chemical structure | PDIA3 Protein, Human, Recombinant (His) molecular weight
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