PDIA3 Protein, Human, Recombinant (His)

Name: PDIA3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00935
Price: 112 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein) Copy Product Info

Synonyms: Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein

Catalog No. TMPJ-00935 Copy Product Info

PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$112	-	In Stock
10 µg	$183	-	In Stock
20 µg	$292	7-10 days	7-10 days
50 µg	$545	-	In Stock
100 µg	$813	-	In Stock
200 µg	$1,190	7-10 days	7-10 days
500 µg	$2,070	-	In Stock
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 85% as determined by reducing SDS-PAGE. (QC verified)

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P30101
Amino Acid	Ser25-Leu505
Construction	Ser25-Leu505
Protein Purity	Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 7.5.
Synonyms	Protein disulfide-isomerase A3, PDIA3 protein, ER protein 57, Disulfide isomerase ER-60, 58 kDa glucose-regulated protein
Research Background	PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

Chemical Properties

Molecular Weight

60 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.