Anti-ATAD2 Polyclonal Antibody is a Rabbit antibody targeting ATAD2. Anti-ATAD2 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.

IgG

Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep)

Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-ATAD2 Polyclonal Antibody, Unconjugated (TMAB-00157) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.

IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500

Polyclonal

KLH conjugated synthetic peptide: human ATAD2

Human

ATAD2

ATPase family AAA domain-containing protein 2

Estrogen,Bromodomains,Bromodomain containing,ATPases,Other Chaperones

May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.