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Panaxatriol

Name: Panaxatriol
Brand: TargetMol
SKU: T2804
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2804Cas No. 32791-84-7

Alias Panaxtriol

Panaxatriol (Panaxtriol) can relieve myelosuppression induced by radiation injury.

Panaxatriol

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Purity: 99.95%

Catalog No. T2804Alias PanaxtriolCas No. 32791-84-7

Panaxatriol (Panaxtriol) can relieve myelosuppression induced by radiation injury.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$30	In Stock	In Stock
25 mg	$48	In Stock	In Stock
50 mg	$78	In Stock	In Stock
100 mg	$113	In Stock	In Stock
500 mg	$273	-	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.95%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Panaxatriol AI Summary

Panaxatriol demonstrates notable bioactivity in inhibiting growth across various human cancer cell lines, as evidenced by the NCI human tumor cell line growth inhibition assay. The compound shows effective GI50 values ranging from approximately 2,000 nM to over 19,000 nM, indicating its varying levels of potency in different cancer types, including renal, breast, lung, leukemia, prostate, central nervous system, melanoma, ovarian, and colon cancers. Furthermore, Panaxatriol exhibits cytoprotective activity against OGD/reperfusion-induced injury in Sprague-Dawley rat cardiomyocytes, with increased effectiveness at higher concentrations (0.1 μM, 1 μM, and 10 μM). In a rat model of LAD coronary artery ligation-induced ischemia/reperfusion, the compound also demonstrates cardioprotective activity, significantly reducing the infarct size of the left ventricle at a dosage of 40 mg/kg when administered twice daily for three days..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Panaxatriol (Panaxtriol) can relieve myelosuppression induced by radiation injury.
Synonyms	Panaxtriol

Chemical Properties

Molecular Weight	476.73
Formula	C₃₀H₅₂O₄
Cas No.	32791-84-7
Smiles	CC12CCC(C1C(O)CC1C3(C)CCC(O)C(C)(C)C3C(O)CC21C)C1(C)CCCC(C)(C)O1
Relative Density.	1.068 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 31.25 mg/mL (65.55 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (5.24 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0976 mL	10.4881 mL	20.9762 mL	104.8812 mL
5 mM	0.4195 mL	2.0976 mL	4.1952 mL	20.9762 mL
10 mM	0.2098 mL	1.0488 mL	2.0976 mL	10.4881 mL
20 mM	0.1049 mL	0.5244 mL	1.0488 mL	5.2441 mL
50 mM	0.0420 mL	0.2098 mL	0.4195 mL	2.0976 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc