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Granotapide

Name: Granotapide
Brand: TargetMol
SKU: T31992
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T31992Cas No. 594842-13-4

Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, and hypertension.

Granotapide

🥰Excellent

Purity: 99.79%

Catalog No. T31992Cas No. 594842-13-4

Pack Size	Price	Availability
1 mg	$210	In Stock
5 mg	$530	In Stock
10 mg	$766	In Stock
25 mg	$1,180	In Stock
50 mg	$1,590	In Stock
100 mg	$2,150	In Stock
500 mg	$4,290	In Stock
1 mL x 10 mM (in DMSO)	$778	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.79%

Resource Download

COA FNMR HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	718.71
Formula	C₃₉H₃₇F₃N₂O₈
Cas No.	594842-13-4
Smiles	C(COC(CC1=CC(C(N(C)C)=O)=C(NC(=O)C2=C(C=CC=C2)C3=CC=C(C(F)(F)F)C=C3)C=C1)=O)(C(OCC)=O)(C(OCC)=O)C4=CC=CC=C4
Relative Density.	1.285 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (38.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3914 mL	6.9569 mL	13.9138 mL	69.5691 mL
5 mM	0.2783 mL	1.3914 mL	2.7828 mL	13.9138 mL
10 mM	0.1391 mL	0.6957 mL	1.3914 mL	6.9569 mL
20 mM	0.0696 mL	0.3478 mL	0.6957 mL	3.4785 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc