IL-36 gamma Protein, Mouse, Recombinant

Name: IL-36 gamma Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPJ-01234
Price: 148 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Interleukin-36 γ, Interleukin-36 gamma, Interleukin-1 homolog 1, IL36G, IL-36 γ, IL-1RP2, IL-1-related protein 2, IL-1H1, IL-1F9, IL-1 ε, IL-1 epsilon) Copy Product Info

Synonyms: Interleukin-36 γ, Interleukin-36 gamma, Interleukin-1 homolog 1, IL36G, IL-36 γ, IL-1RP2, IL-1-related protein 2, IL-1H1, IL-1F9, IL-1 ε, IL-1 epsilon

Catalog No. TMPJ-01234 Copy Product Info

Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

Pack Size	Price	USA Stock	Global Stock
5 µg	$148	-	In Stock
10 µg	$247	-	In Stock
20 µg	$396	7-10 days	7-10 days
50 µg	$745	7-10 days	7-10 days
100 µg	$1,060	7-10 days	7-10 days
200 µg	$1,530	7-10 days	7-10 days
500 µg	$2,480	7-10 days	7-10 days
1 mg	$3,720	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	Q8R460
Amino Acid	Gly13-Ser164
Construction	Gly13-Ser164
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Histidine-HCl, 10% Trehalose, 0.05% Tween 80, pH5.5.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Interleukin-36 γ, Interleukin-36 gamma, Interleukin-1 homolog 1, IL36G, IL-36 γ, IL-1RP2, IL-1-related protein 2, IL-1H1, IL-1F9, IL-1 ε, IL-1 epsilon
Research Background	Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

Chemical Properties

Molecular Weight

17 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.