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Anti-CCR5 Polyclonal Antibody

😃Good
Catalog No. TMAB-00325
Alias IDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5

Anti-CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR5. Anti-CCR5 Polyclonal Antibody can be used in WB.

Anti-CCR5 Polyclonal Antibody

Anti-CCR5 Polyclonal Antibody

😃Good
Catalog No. TMAB-00325Alias IDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5
Anti-CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR5. Anti-CCR5 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3747-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR5. Anti-CCR5 Polyclonal Antibody can be used in WB.
AliasIDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
Lane 1: Human THP-1 cell lysates
Lane 2: Human U937 cell lysates
Primary: Anti-CCR-5 (TMAB-00325) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 43 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CCR-5
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
GPCR,Chemokines,HIV-related,Beta Chemokine Rec. (CCR),Macrophage / Inflamm.,Host Virus Interaction,Alzheimer's disease,GPCR
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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