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1,4-DPCA ethyl ester

🥰Excellent
Catalog No. T36796Cas No. 86443-19-8

1,4-DPCA ethyl ester is a form of 1,4-DPCA modified to ethyl ester, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.

1,4-DPCA ethyl ester

1,4-DPCA ethyl ester

🥰Excellent
Purity: 99.54%
Catalog No. T36796Cas No. 86443-19-8
1,4-DPCA ethyl ester is a form of 1,4-DPCA modified to ethyl ester, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$48In Stock
10 mg$81In Stock
25 mg$156In Stock
50 mg$263In Stock
100 mg$445In Stock
200 mg$649In Stock
1 mL x 10 mM (in DMSO)$53In Stock
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Purity:99.54%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
1,4-DPCA ethyl ester is a form of 1,4-DPCA modified to ethyl ester, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.
Chemical Properties
Molecular Weight268.27
FormulaC15H12N2O3
Cas No.86443-19-8
SmilesO=C(OCC)C1=CNC=2C3=NC=CC=C3C=CC2C1=O
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (37.28 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.73 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7276 mL18.6379 mL37.2759 mL186.3794 mL
5 mM0.7455 mL3.7276 mL7.4552 mL37.2759 mL
10 mM0.3728 mL1.8638 mL3.7276 mL18.6379 mL
20 mM0.1864 mL0.9319 mL1.8638 mL9.3190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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