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SIRP gamma Protein, Human, Recombinant (His & Avi)
(Synonyms: SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1) Copy Product InfoSynonyms: SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1
Catalog No. TMPK-00250 Copy Product Info
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $44 | - | In Stock | |
| 10 µg | $68 | - | In Stock | |
| 20 µg | $108 | 7-10 days | 7-10 days | |
| 50 µg | $198 | 7-10 days | 7-10 days | |
| 100 µg | $347 | - | In Stock | |
| 200 µg | $628 | 7-10 days | 7-10 days | |
| 500 µg | $1,400 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human SIRP Gamma, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CD47, hFc Tag with the EC50 of 2.46μg/ml determined by ELISA. |
| Description | Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | Q9P1W8 |
| Construction | Glu29-Pro360 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1 |
| Research Background | Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| Molecular Weight | 39.7 kDa (predicted). Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: SIRP gamma Protein, Human, Recombinant (His & Avi) chemical structure | SIRP gamma Protein, Human, Recombinant (His & Avi) molecular weight
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