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TFPI2 Protein, Mouse, Recombinant (His)

TargetMol | SPR
Catalog No. TMPY-02329

TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.87 kDa and the accession number is O35536.

TFPI2 Protein, Mouse, Recombinant (His)

TFPI2 Protein, Mouse, Recombinant (His)

TargetMol | SPR
Catalog No. TMPY-02329
TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.87 kDa and the accession number is O35536.
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100 μg$7007-10 days
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Product Information

Biological Activity
Activity testing is not tested. It is theoretically active, but we cannot guarantee it.
Description
TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.87 kDa and the accession number is O35536.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberO35536
Synonyms
tissue factor pathway inhibitor 2,PP5/TFPI-2,AV000670
Construction
Leu23-Ser230
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight24.87 kDa (Predicted); 35-50 kDa (Due to glycosylation)
EndotoxinLess than 1EU per μg by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens.

Dose Conversion

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