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Anti-PAX6 Antibody (9N406)
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Catalog No. TMAC-03077
Alias PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2
Anti-PAX6 Antibody (9N406) is a Rabbit antibody targeting PAX6. Anti-PAX6 Antibody (9N406) can be used in WB,IHC,FCM.
Anti-PAX6 Antibody (9N406)
Anti-PAX6 Antibody (9N406)
😃Good
Catalog No. TMAC-03077Alias PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2
Anti-PAX6 Antibody (9N406) is a Rabbit antibody targeting PAX6. Anti-PAX6 Antibody (9N406) can be used in WB,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PAX6 Antibody (9N406) is a Rabbit antibody targeting PAX6. Anti-PAX6 Antibody (9N406) can be used in WB,IHC,FCM. |
| Synonyms | PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PAX6 on mouse eyes lysates using anti-PAX6 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat eyes tissue using anti-PAX6 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse eyes tissue using anti-PAX6 antibody. Counter stained with hematoxylin. 4. Flow cytometric analysis of SH-SY-5Y cells with PAX6 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the ssecondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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