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P-SCN-Bn-DOTA

Catalog No. T38681 CAS 127985-74-4

p-SCN-Bn-DOTA is a chelator that simultaneously chelates radionuclides and connects monoclonal antibodies. It can be used as a tracer for radio-guided surgery and can be used for radio-immunoassay studies of tumors.

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P-SCN-Bn-DOTA, CAS 127985-74-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 83.00
5 mg	In stock	$ 197.00
10 mg	In stock	$ 328.00
25 mg	In stock	$ 553.00
50 mg	In stock	$ 789.00
100 mg	In stock	$ 1,070.00
1 mL * 10 mM (in DMSO)	In stock	$ 249.00

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Purity: 95.03%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	p-SCN-Bn-DOTA is a chelator that simultaneously chelates radionuclides and connects monoclonal antibodies. It can be used as a tracer for radio-guided surgery and can be used for radio-immunoassay studies of tumors.
In vitro	p-SCN-Bn-DOTA forms complexes with five different metal ions: Lu(III), Gd(III), In(III), Y(III), and Cu(II).[2]

Molecular Weight	551.61
Formula	C24H33N5O8S
CAS No.	127985-74-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Vera DRB, et, al. Preclinical evaluation of (177)lu-nimotuzumab: a potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors. Cancer Biother Radiopharm. 2011 Jun;26(3):287-97. 2. Giannini G, et, al. Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors. Bioorg Med Chem. 2019 Aug 1;27(15):3248-3253.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

P-SCN-Bn-DOTA 127985-74-4 Others p SCN Bn DOTA pSCNBnDOTA inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.