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Bermoprofen

Name: Bermoprofen
Brand: TargetMol
SKU: T14546
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14546Cas No. 78499-27-1

Alias AJ-1590, AD-1590

Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.

Bermoprofen

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Purity: 99.28%

Catalog No. T14546Alias AJ-1590, AD-1590Cas No. 78499-27-1

Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$74	-	In Stock
5 mg	$178	-	In Stock
10 mg	$298	-	In Stock
25 mg	$596	-	In Stock
50 mg	$798	-	In Stock
100 mg	$1,060	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.28%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.
In vitro	Bermoprofen is coated onto immediate-release granules (IRG) with a film solution composed of ethyl cellulose and hydroxypropyl methylcellulose (3:2) by spraying, thereby obtaining three types of sustained-release granules (RRGs) to prolong its duration of action and reduce its side effects[1].
In vivo	In male albino rabbits weighing 2.3-3 kg, Bermoprofen (0.04, 0.4, 0.1 mg/kg; oral; administered 1 hour after intravenous injection of LPS) significantly inhibited the rise in rectal temperature[2].
Synonyms	AJ-1590, AD-1590

Chemical Properties

Molecular Weight	296.32
Formula	C₁₈H₁₆O₄
Cas No.	78499-27-1
Smiles	O=C(O)C(C1=CC=C2OC3=CC=C(C=C3CC(=O)C2=C1)C)C
Relative Density.	1.1874 g/cm3 (Estimated)

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (269.98 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.14 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3747 mL	16.8737 mL	33.7473 mL	168.7365 mL
5 mM	0.6749 mL	3.3747 mL	6.7495 mL	33.7473 mL
10 mM	0.3375 mL	1.6874 mL	3.3747 mL	16.8737 mL
20 mM	0.1687 mL	0.8437 mL	1.6874 mL	8.4368 mL
50 mM	0.0675 mL	0.3375 mL	0.6749 mL	3.3747 mL
100 mM	0.0337 mL	0.1687 mL	0.3375 mL	1.6874 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc