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Bermoprofen

🥰Excellent
TargetMol
Catalog No. T14546Cas No. 78499-27-1
Alias AJ-1590, AD-1590

Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.

Bermoprofen

Bermoprofen

🥰Excellent
TargetMol
Purity: 99.28%
Catalog No. T14546Alias AJ-1590, AD-1590Cas No. 78499-27-1
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.
Pack SizePriceAvailabilityQuantity
1 mg$123In Stock
5 mg$297In Stock
10 mg$496In Stock
25 mg$993In Stock
50 mg$1,330In Stock
100 mg$1,780In Stock
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Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.28%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.
In vitro
Bermoprofen is coated onto immediate-release granules (IRG) with a film solution composed of ethyl cellulose and hydroxypropyl methylcellulose (3:2) by spraying, thereby obtaining three types of sustained-release granules (RRGs) to prolong its duration of action and reduce its side effects[1].
In vivo
In male albino rabbits weighing 2.3-3 kg, Bermoprofen (0.04, 0.4, 0.1 mg/kg; oral; administered 1 hour after intravenous injection of LPS) significantly inhibited the rise in rectal temperature[2].
SynonymsAJ-1590, AD-1590
Chemical Properties
Molecular Weight296.32
FormulaC18H16O4
Cas No.78499-27-1
SmilesO=C(O)C(C1=CC=C2OC3=CC=C(C=C3CC(=O)C2=C1)C)C
Relative Density.1.1874 g/cm3 (Estimated)
ColorYellow
AppearanceOil
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (269.98 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.14 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3747 mL16.8737 mL33.7473 mL168.7365 mL
5 mM0.6749 mL3.3747 mL6.7495 mL33.7473 mL
10 mM0.3375 mL1.6874 mL3.3747 mL16.8737 mL
20 mM0.1687 mL0.8437 mL1.6874 mL8.4368 mL
50 mM0.0675 mL0.3375 mL0.6749 mL3.3747 mL
100 mM0.0337 mL0.1687 mL0.3375 mL1.6874 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

BermoprofenAD1590AD 1590
Related Tags: buy Bermoprofen | purchase Bermoprofen | Bermoprofen cost | order Bermoprofen | Bermoprofen chemical structure | Bermoprofen in vivo | Bermoprofen in vitro | Bermoprofen formula | Bermoprofen molecular weight
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