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PAL-4

Name: PAL-4
Brand: TargetMol
SKU: T9733
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9733Cas No. 2609594-35-4

Alias 1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]-

PAL-4 stimulates the activity of LYPLAL1, a poorly characterized serine hydrolase with complex genetic links to human metabolic traits.

PAL-4

🥰Excellent

Purity: 98.08%

Catalog No. T9733Alias 1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]-Cas No. 2609594-35-4

PAL-4 stimulates the activity of LYPLAL1, a poorly characterized serine hydrolase with complex genetic links to human metabolic traits.

Pack Size	Price	Availability
1 mg	$89	In Stock
5 mg	$202	In Stock
10 mg	$298	In Stock
25 mg	$476	In Stock
50 mg	$678	In Stock
100 mg	$912	In Stock
200 mg	$1,190	In Stock
1 mL x 10 mM (in DMSO)	$226	In Stock

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Batch Information

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Purity:98.08%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	PAL-4 stimulates the activity of LYPLAL1, a poorly characterized serine hydrolase with complex genetic links to human metabolic traits.
Synonyms	1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]-

Chemical Properties

Molecular Weight	422.91
Formula	C₁₇H₁₅ClN₄O₃S₂
Cas No.	2609594-35-4
Smiles	S(=O)(=O)(N1N=C(SCC2=CC=C(Cl)C=C2)N=C1N)C=3C=C4C(=CC3)OCC4
Relative Density.	1.62 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (118.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3646 mL	11.8228 mL	23.6457 mL	118.2285 mL
5 mM	0.4729 mL	2.3646 mL	4.7291 mL	23.6457 mL
10 mM	0.2365 mL	1.1823 mL	2.3646 mL	11.8228 mL
20 mM	0.1182 mL	0.5911 mL	1.1823 mL	5.9114 mL
50 mM	0.0473 mL	0.2365 mL	0.4729 mL	2.3646 mL
100 mM	0.0236 mL	0.1182 mL	0.2365 mL	1.1823 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc