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Anti-15-PGDH Antibody-FITC (8A987)
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Catalog No. TMAY-01752F
Alias hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH
Anti-15-PGDH Antibody-FITC (8A987) is a FITC-conjugated Rabbit antibody targeting 15-PGDH. Anti-15-PGDH Antibody-FITC (8A987) can be used in FCM.
Anti-15-PGDH Antibody-FITC (8A987)
Anti-15-PGDH Antibody-FITC (8A987)
😃Good
Catalog No. TMAY-01752FAlias hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH
Anti-15-PGDH Antibody-FITC (8A987) is a FITC-conjugated Rabbit antibody targeting 15-PGDH. Anti-15-PGDH Antibody-FITC (8A987) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $105 | 7-10 days | |
| 100 T | $211 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-15-PGDH Antibody-FITC (8A987) is a FITC-conjugated Rabbit antibody targeting 15-PGDH. Anti-15-PGDH Antibody-FITC (8A987) can be used in FCM. |
| Alias | hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8A987 |
| Reactivity | Human |
| Verified Activity | Human HPGD expression in Jurkat cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human HPGD / 15-PGDH (rh HPGD / 15-PGDH; TMPY-01264; NP_000851.2; Met1-Gln266) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | 15-hydroxyprostaglandin dehydrogenase [NAD+], also known as Prostaglandin dehydrogenase 1, HPGD, and PGDH1, is a member of the short-chain dehydrogenases/reductases (SDR) family. Prostaglandins (PGs) play a key role in the onset of labor in many species and regulate uterine contractility and cervical dilatation. Therefore, the regulation of prostaglandin output by PG synthesizing and metabolizing enzymes in the human myometrium may determine uterine activity patterns in human labor both at preterm and at term. Prostaglandin dehydrogenase (PGDH) metabolizes prostaglandins (PGs) to render them inactive. HPGD is down-regulated by cortisol, dexamethasone, and betamethasone and down-regulated in colon cancer. It is up-regulated by TGFB1. HPGD contributes to the regulation of events that are under the control of prostaglandin levels. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. and inhibits in vivo proliferation of colon cancer cells. Defects in HPGD are the cause of primary hypertrophic osteoarthropathy autosomal recessive (PHOAR), cranio-osteoarthropathy (COA), and isolated congenital nail clubbing. |
| Conjucates | FITC |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human HPGD / 15-PGDH protein (TMPY-01264) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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