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CXCL14 Protein, Human, Recombinant

Catalog No. TMPY-03781
Synonyms: SCYB14, MIP-2g, MIP2G, KS1, BRAK, NJAC, KEC, chemokine (C-X-C motif) ligand 14, BMAC

CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CXCL14 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
20 μg 5 days $ 212.00
100 μg 5 days $ 539.00
1 mg 5 days $ 3,520.00
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Biological Description
Technical Params
Product Properties
Description CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
Species Human
Expression System E. coli
Tag Tag Free
Accession Number O95715
Synonyms SCYB14, MIP-2g, MIP2G, KS1, BRAK, NJAC, KEC, chemokine (C-X-C motif) ligand 14, BMAC
Construction A DNA sequence encoding human CXCL14 (O95715) (Ser35-Glu111) was expressed with a N-terminal Met.
Protein Purity > 90 % as determined by SDS-PAGE
Molecular Weight 9.4 kDa (predicted)
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile 100mM NaH2PO4, 1M NaCl, pH 6. 5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.

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Keywords

CXCL14 Protein, Human, Recombinant SCYB14 MIP-2g MIP2G KS1 BRAK KS-1 NJAC KS 1 SCYB 14 KEC chemokine (C-X-C motif) ligand 14 SCYB-14 BMAC recombinant recombinant-proteins proteins protein

 

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