Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC IRAK4 Degrader-2 (Compound 9) is a PROTAC-based degrader that potently reduces IRAK4 levels, achieving a DC50 of 151 nM in peripheral blood mononuclear cells (PBMCs). It also notably decreases IRAK4 protein levels with a DC50 of 36 nM in the same cell type and inhibits several cytokines in PBMCs [1].
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Description | PROTAC IRAK4 Degrader-2 (Compound 9) is a PROTAC-based degrader that potently reduces IRAK4 levels, achieving a DC50 of 151 nM in peripheral blood mononuclear cells (PBMCs). It also notably decreases IRAK4 protein levels with a DC50 of 36 nM in the same cell type and inhibits several cytokines in PBMCs [1]. |
Molecular Weight | 1086.28 |
Formula | C57H68FN11O8S |
CAS No. | 2374122-27-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC IRAK4 degrader-2 2374122-27-5 inhibitor inhibit