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Boc-NH-PEG23-CH2CH2N3 is a PEG-based linker used in PROTACs to connect two vital ligands necessary for forming PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
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500 mg | Inquiry | Backorder |
Description | Boc-NH-PEG23-CH2CH2N3 is a PEG-based linker used in PROTACs to connect two vital ligands necessary for forming PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 1199.42 |
Formula | C53H106N4O25 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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