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Prodigiosin
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Catalog No. T16580Cas No. 82-89-3
Alias Prodigiosine, NSC47147, NSC 47147
Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities.
Prodigiosin
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Purity: 99.99%
Catalog No. T16580Alias Prodigiosine, NSC47147, NSC 47147Cas No. 82-89-3
Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $40 | - | In Stock | |
| 250 μg | $73 | - | In Stock | |
| 500 μg | $123 | - | In Stock | |
| 1 mg | $197 | - | In Stock | |
| 5 mg | $413 | - | In Stock | |
| 10 mg | $619 | - | In Stock | |
| 25 mg | $965 | - | In Stock | |
| 50 mg | $1,280 | - | In Stock | |
| 100 mg | $1,750 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $455 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.99%
Appearance:Solid
Color:Red
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities. |
| In vitro | Prodigiosin treatment (25–500 nM; 24 hours) reduced viability and induced apoptosis in breast cancer cell lines MDA-MB-231 and MDA-MB-468, while decreasing levels of phosphorylated LRP6 and DVL2, active β-catenin, and total β-catenin. Prodigiosin significantly inhibits phosphorylation of GSK3β at Ser9 in HEK293T cells [1]. Prodigiosin inhibits the growth of chytrid fungi Batrachochytrium dendrobatidis and B. salamandrivorans with MIC values of 10 μM and 50 μM, respectively[2]. |
| In vivo | Prodigiosin (5 mg/kg; intraperitoneal injection; twice weekly; for 3 weeks) significantly inhibited tumor growth, reduced tumor cell density, and decreased expression of the proliferation marker Ki-67 [1]. |
| Synonyms | Prodigiosine, NSC47147, NSC 47147 |
| Molecular Weight | 323.44 |
| Formula | C20H25N3O |
| Cas No. | 82-89-3 |
| Smiles | N=1C(=CC=2NC(=CC2OC)C3=CC=CN3)C=C(C1C)CCCCC |
| Relative Density. | 1.12 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (61.84 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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