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Prodigiosin
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Catalog No. T16580Cas No. 82-89-3
Alias Prodigiosine, NSC47147, NSC 47147
Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities.
Prodigiosin
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Purity: 99.99%
Catalog No. T16580Alias Prodigiosine, NSC47147, NSC 47147Cas No. 82-89-3
Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $40 | - | In Stock | |
| 250 μg | $73 | - | In Stock | |
| 500 μg | $123 | - | In Stock | |
| 1 mg | $197 | - | In Stock | |
| 5 mg | $413 | - | In Stock | |
| 10 mg | $619 | - | In Stock | |
| 25 mg | $965 | - | In Stock | |
| 50 mg | $1,280 | - | In Stock | |
| 100 mg | $1,750 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $455 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.99%
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities. |
| In vitro | Prodigiosin treatment (25–500 nM; 24 hours) reduced viability and induced apoptosis in breast cancer cell lines MDA-MB-231 and MDA-MB-468, while decreasing levels of phosphorylated LRP6 and DVL2, active β-catenin, and total β-catenin. Prodigiosin significantly inhibits phosphorylation of GSK3β at Ser9 in HEK293T cells [1]. Prodigiosin inhibits the growth of chytrid fungi Batrachochytrium dendrobatidis and B. salamandrivorans with MIC values of 10 μM and 50 μM, respectively[2]. |
| In vivo | Prodigiosin (5 mg/kg; intraperitoneal injection; twice weekly; for 3 weeks) significantly inhibited tumor growth, reduced tumor cell density, and decreased expression of the proliferation marker Ki-67 [1]. |
| Synonyms | Prodigiosine, NSC47147, NSC 47147 |
| Molecular Weight | 323.44 |
| Formula | C20H25N3O |
| Cas No. | 82-89-3 |
| Smiles | N=1C(=CC=2NC(=CC2OC)C3=CC=CN3)C=C(C1C)CCCCC |
| Relative Density. | 1.12 g/cm3 (Predicted) |
| Color | Red |
| Appearance | Solid |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (61.84 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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