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FGF-1 Protein, Mouse, Rat, Recombinant

Catalog No. TMPY-01089
Synonyms: fibroblast growth factor 1 (acidic)

aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.References

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
FGF-1 Protein, Mouse, Rat, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 88.00
100 μg 5 days $ 306.00
1 mg 5 days $ 2,000.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.References
Species Mouse,Rat
Expression System E. coli
Tag Tag Free
Accession Number P61148
Synonyms fibroblast growth factor 1 (acidic)
Construction A DNA sequence encoding the mature form of mouse / rat FGF1 (NP_034327.1) (Phe16-Asp155) was expressed. Mouse and Rat FGF1 sequences are identical.
Protein Purity > 90 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 16 kDa
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile 50mM Na2SO4, 0. 5mM DTT, 1mM EDTA, 20mM Tris, pH 7.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.References

References and Literature

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Keywords

FGF-1 Protein, Mouse, Rat, Recombinant fibroblast growth factor 1 acidic fibroblast growth factor 1 (acidic) recombinant recombinant-proteins proteins protein

 

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