VEGFD Protein, Human, Recombinant (His)

Name: VEGFD Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01008
Rating: 4.5 (1 reviews)

(Synonyms: VEGF-D, VEGFD, c-fos induced growth factor (vascular endothelial growth factor D)) Copy Product Info

Synonyms: VEGF-D, VEGFD, c-fos induced growth factor (vascular endothelial growth factor D)

Catalog No. TMPY-01008 Copy Product Info

Purity: 98%

VEGFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is O43915.

Pack Size	Price	USA Stock	Global Stock
5 µg	$66	7-10 days	7-10 days
10 µg	$106	-	In Stock
20 µg	$153	7-10 days	7-10 days
50 µg	$242	7-10 days	7-10 days
100 µg	$346	7-10 days	7-10 days
200 µg	$585	7-10 days	7-10 days
500 µg	$1,160	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1.Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is 0.3‑1.6 μg/mL. 2.Captured VEGFR3/FLT4 Protein, Human on proA Chip can bind VEGF-D with an affinity constant of 39.03 nM as determined in a SPR assay (Routinely tested).
Description	VEGFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is O43915.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	O43915
Construction	A DNA sequence encoding the mature form of human VEGFD (NP_004460.1) corresponding to amino acid (Phe 93-Ser 201) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Phe 93
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	VEGF-D, VEGFD, c-fos induced growth factor (vascular endothelial growth factor D)
Research Background	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

Chemical Properties

Molecular Weight

13.6 kDa (predicted); 20-22 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.