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IL-1 alpha/IL-1A Protein, Rat, Recombinant (CHO) is expressed in CHO Cells. The accession number is P16598-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $170 | 7-10 days | |
50 μg | $622 | 7-10 days | |
1 mg | $4,750 | 7-10 days |
Biological Activity | ED 50 < 5.0 pg/ml, measured in a proliferation assay using D10S cells. |
Description | IL-1 alpha/IL-1A Protein, Rat, Recombinant (CHO) is expressed in CHO Cells. The accession number is P16598-1. |
Species | Rat |
Expression System | CHO Cells |
Tag | Tag Free |
Accession Number | P16598-1 |
Synonyms | interleukin 1 alpha,IL-1α,IL1F1,IL1-ALPHA,IL-1A,IL1A,IL-1 alpha,IL1 |
Construction | Ala116-Ser270 |
Protein Purity | > 95% as determined by SDS-PAGE |
Molecular Weight | 17~22 kDa (Reducing conditions) |
Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. |
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