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PF-610355 HCl
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Catalog No. T16509L
Alias PF-610355 HCl(4033-27-6 Free base), PF610355 HCl, PF-610,355 HCl, PF-00610355 HCl
PF-610355 HCl is a selective and potent β2-adrenergic receptor agonist, a bronchodilator, and is used in the study of asthma and chronic obstructive pulmonary disease.
PF-610355 HCl
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Purity: 97.97%
Catalog No. T16509LAlias PF-610355 HCl(4033-27-6 Free base), PF610355 HCl, PF-610,355 HCl, PF-00610355 HCl
PF-610355 HCl is a selective and potent β2-adrenergic receptor agonist, a bronchodilator, and is used in the study of asthma and chronic obstructive pulmonary disease.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $95 | In Stock | In Stock | |
| 5 mg | $210 | In Stock | In Stock | |
| 10 mg | $315 | In Stock | In Stock | |
| 25 mg | $585 | In Stock | In Stock | |
| 50 mg | $856 | In Stock | In Stock | |
| 100 mg | $1,125 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:97.97%
ee:100%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PF-610355 HCl is a selective and potent β2-adrenergic receptor agonist, a bronchodilator, and is used in the study of asthma and chronic obstructive pulmonary disease. |
| In vivo | PF-610355 HCl is a once-daily, long-acting inhaled β2-adrenoceptor agonist. Oral bioavailability is limited due to low intestinal absorption and high first-pass metabolism, and further studies are warranted.The short half-life of PF-610355 HCl (Clint = 33 (μL/min)/mg) suggests an unconjugated intrinsic clearance of more than 10,000 (mL/min)/kg.Overall, PF-610355 HCl demonstrates desirable inhalant pharmacokinetic properties. [1] |
| Synonyms | PF-610355 HCl(4033-27-6 Free base), PF610355 HCl, PF-610,355 HCl, PF-00610355 HCl |
| Molecular Weight | 479.87 |
| Formula | C19H22ClN7O6 |
| Smiles | O=C1C2=C(NC(N)=N1)NCC(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)=N2.Cl |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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