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2-(Pyridyldithio)ethylamine hydrochloride

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Catalog No. T19106Cas No. 106139-15-5
Alias (S)-2-Pyridylthio Cysteamine Hydrochloride

2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) is a disulfide intercalating cross-linking reagent.

2-(Pyridyldithio)ethylamine hydrochloride

2-(Pyridyldithio)ethylamine hydrochloride

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Purity: 99.66%
Catalog No. T19106Alias (S)-2-Pyridylthio Cysteamine HydrochlorideCas No. 106139-15-5
2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) is a disulfide intercalating cross-linking reagent.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$40In Stock-
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.66%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) is a disulfide intercalating cross-linking reagent.
In vitro
2-(Pyridyldithio)ethylamine hydrochloride can be used to prepare the drug-octreotide conjugate.
Synonyms(S)-2-Pyridylthio Cysteamine Hydrochloride
Chemical Properties
Molecular Weight222.76
FormulaC7H11ClN2S2
Cas No.106139-15-5
SmilesCl.NCCSSc1ccccn1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 32 mg/mL (143.65 mM), Sonication is recommended.
H2O: 50 mg/mL (224.46 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM4.4891 mL22.4457 mL44.8914 mL224.4568 mL
5 mM0.8978 mL4.4891 mL8.9783 mL44.8914 mL
10 mM0.4489 mL2.2446 mL4.4891 mL22.4457 mL
20 mM0.2245 mL1.1223 mL2.2446 mL11.2228 mL
50 mM0.0898 mL0.4489 mL0.8978 mL4.4891 mL
100 mM0.0449 mL0.2245 mL0.4489 mL2.2446 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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