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DBCO-PEG4-Biotin

Name: DBCO-PEG4-Biotin
Brand: TargetMol
SKU: T15069
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15069Cas No. 1255942-07-4

Alias ADIBO-NH-PEG2-Biotin

DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).

DBCO-PEG4-Biotin

🥰Excellent

Purity: 98.90%

Catalog No. T15069Alias ADIBO-NH-PEG2-BiotinCas No. 1255942-07-4

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$89	In Stock
10 mg	$138	In Stock

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Batch Information

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Purity:98.90%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).
In vitro	The alkyne group reacts with the azide moiety in a copper-free Click Chemistry reaction to form a stable triazole linkage.[1]
Synonyms	ADIBO-NH-PEG2-Biotin

Chemical Properties

Molecular Weight	749.92
Formula	C₃₉H₅₁N₅O₈S
Cas No.	1255942-07-4
Smiles	C(CCCC(NCCOCCOCCOCCOCCC(NCCC(=O)N1C=2C(C#CC=3C(C1)=CC=CC3)=CC=CC2)=O)=O)[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H]
Relative Density.	1.30 g/cm3 (Predicted)
Color	Yellow
Appearance	Viscous

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 74.99 mg/mL (100 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3335 mL	6.6674 mL	13.3348 mL	66.6738 mL
5 mM	0.2667 mL	1.3335 mL	2.6670 mL	13.3348 mL
10 mM	0.1333 mL	0.6667 mL	1.3335 mL	6.6674 mL
20 mM	0.0667 mL	0.3334 mL	0.6667 mL	3.3337 mL
50 mM	0.0267 mL	0.1333 mL	0.2667 mL	1.3335 mL
100 mM	0.0133 mL	0.0667 mL	0.1333 mL	0.6667 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DBCO-PEG4-Biotin