Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-CD19 Antibody-PE (1T602) is a PE-conjugated Mouse antibody targeting CD19. Anti-CD19 Antibody-PE (1T602) can be used in FCM.
Description | Anti-CD19 Antibody-PE (1T602) is a PE-conjugated Mouse antibody targeting CD19. Anti-CD19 Antibody-PE (1T602) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1T602 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD19 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD19 and FITC-conjugated anti-Human CD3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD19 (rh CD19; TMPY-01949; P15391-1; Met1-Lys291) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | PE |
Others Formats | Unconjugated/Biotin/FITC |
Antibody Types Available | 4 |
Immunogen | Recombinant Human CD19 Protein (TMPY-01949) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.