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Sovaprevir

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Catalog No. T28830Cas No. 1001667-23-7
Alias ACH-1625, ACH1625, ACH-0141625, ACH0141625, ACH 1625, ACH 0141625

Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.

Sovaprevir

Sovaprevir

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Purity: 99.89%
Catalog No. T28830Alias ACH-1625, ACH1625, ACH-0141625, ACH0141625, ACH 1625, ACH 0141625Cas No. 1001667-23-7
Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$280In StockIn Stock
5 mg$689In StockIn Stock
10 mg$983In StockIn Stock
25 mg$1,460In StockIn Stock
50 mg$1,970In StockIn Stock
100 mg$2,650-In Stock
1 mL x 10 mM (in DMSO)$1,090In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.89%
Appearance:Solid
Color:Yellow
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Product Introduction

Sovaprevir AI Summary
Sovaprevir exhibits strong antiviral activity against Hepatitis C virus genotype 1b, with an EC50 value of 11.0 nM, as demonstrated in human Huh-9-13 cells using a replicon assay..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.
SynonymsACH-1625, ACH1625, ACH-0141625, ACH0141625, ACH 1625, ACH 0141625
Chemical Properties
Molecular Weight799.97
FormulaC43H53N5O8S
Cas No.1001667-23-7
SmilesN(C(=O)[C@H]1N(C([C@@H](CC(=O)N2CCCCC2)C(C)(C)C)=O)C[C@H](OC=3C4=C(N=C(C3)C5=CC=CC=C5)C=C(OC)C=C4)C1)[C@@]6(C(NS(=O)(=O)C7CC7)=O)[C@H](C=C)C6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (31.25 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2500 mL6.2502 mL12.5005 mL62.5023 mL
5 mM0.2500 mL1.2500 mL2.5001 mL12.5005 mL
10 mM0.1250 mL0.6250 mL1.2500 mL6.2502 mL
20 mM0.0625 mL0.3125 mL0.6250 mL3.1251 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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