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TPK1 Protein, Human, Recombinant (His)
(Synonyms: THMD5, thiamin pyrophosphokinase 1, PP20, HTPK1) Copy Product InfoSynonyms: THMD5, thiamin pyrophosphokinase 1, PP20, HTPK1
Catalog No. TMPY-04773 Copy Product Info
Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $76 | 7-10 days | 7-10 days | |
| 10 μg | $118 | 7-10 days | 7-10 days | |
| 20 μg | $197 | 7-10 days | 7-10 days | |
| 50 μg | $458 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | AAH68460.1 |
| Construction | A DNA sequence encoding the human TPK1 (AAH68460.1) (Met1-Ser243) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His |
| Protein Purity | > 90 % as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Formulation | Supplied as sterile PBS, pH 7.4. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | THMD5, thiamin pyrophosphokinase 1, PP20, HTPK1 |
| Research Background |
| Molecular Weight | 29.5 kDa (predicted); 27-32 kDa (reducing conditions) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: TPK1 Protein, Human, Recombinant (His) chemical structure | TPK1 Protein, Human, Recombinant (His) molecular weight
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