Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a higher number of differentially expressed genes and increased apoptosis in HCT116 cells [1].
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Description | JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a higher number of differentially expressed genes and increased apoptosis in HCT116 cells [1]. |
Molecular Weight | 968.09 |
Formula | C48H60F3N7O9S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JPS014 TFA Chromatin/Epigenetic DNA Damage/DNA Repair HDAC inhibitor inhibit