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APC

The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion. Mutations in the APC gene may result in colorectal cancer.

  • TAME hydrochloride
    T17311784-03-8
    TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.
    • $30
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  • Apcin A HCL
    T643391683535-53-6
    Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V (HY-130
    • $148
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    TargetMol | Inhibitor Sale
  • TASIN-1 Hydrochloride
    T248551678515-13-3In house
    TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
    • $119
    In Stock
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  • Activated Protein C (390-404), human acetate
    TP1628L
    Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.
    • $157
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    TargetMol | Inhibitor Sale
  • CFM 4
    T22646331458-02-7
    CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the growth of drug-resistant human breast cancer cells.
    • $36
    In Stock
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  • Apcin
    T8561300815-04-7
    Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blockin
    • $40
    In Stock
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  • TAME
    T6693901-47-3
    Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.
    • $46
    Backorder
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  • TASIN-1
    T22632792927-06-1
    TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).
    • $33
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    TargetMol | Inhibitor Sale