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Anti-OMGP Antibody (6D81)
😃Good
Catalog No. TMAY-00540
Alias oligodendrocyte myelin glycoprotein
Anti-OMGP Antibody (6D81) is a Mouse antibody targeting OMGP. Anti-OMGP Antibody (6D81) can be used in ELISA.
Anti-OMGP Antibody (6D81)
Anti-OMGP Antibody (6D81)
😃Good
Catalog No. TMAY-00540Alias oligodendrocyte myelin glycoprotein
Anti-OMGP Antibody (6D81) is a Mouse antibody targeting OMGP. Anti-OMGP Antibody (6D81) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | oligodendrocyte myelin glycoprotein |
| Ig Type | Mouse IgG1 |
| Clone | 6D81 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OMGP (rh OMGP; TMPY-02085; P23515-1; Met1-Pro416). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participates in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting, and myelination are crucial processes involved in brain development and regeneration after injury. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human OMGP protein (TMPY-02085) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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