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Anti-GBA3 Antibody-PE (1I463)
🥰Excellent
Catalog No. TMAY-01921P
Anti-GBA3 Antibody-PE (1I463) is a PE-conjugated Mouse antibody targeting GBA3. Anti-GBA3 Antibody-PE (1I463) can be used in FCM.
Anti-GBA3 Antibody-PE (1I463)
Anti-GBA3 Antibody-PE (1I463)
🥰Excellent
Catalog No. TMAY-01921P
Anti-GBA3 Antibody-PE (1I463) is a PE-conjugated Mouse antibody targeting GBA3. Anti-GBA3 Antibody-PE (1I463) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-GBA3 Antibody-PE (1I463) is a PE-conjugated Mouse antibody targeting GBA3. Anti-GBA3 Antibody-PE (1I463) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 1I463 |
| Reactivity | Human |
| Verified Activity | Human GBA3 expression in Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Mouse anti-GBA3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GBA3 (rh GBA3; TMPY-01579; NP_066024.1; Met1-Leu469) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. |
| Conjucates | PE |
| Immunogen | Recombinant Human GBA3 protein (TMPY-01579) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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