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Anti-Phospho-p53 (Ser33) Polyclonal Antibody (Synonyms: p-p53 (Ser33), p-p53 (S33), p53 (p-Ser33), p53 (p-S33...)

Catalog No. TMAC-02997 Copy Product Info
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Anti-Phospho-p53 (Ser33) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser33). Anti-Phospho-p53 (Ser33) Polyclonal Antibody can be used in IF,WB.

Anti-Phospho-p53 (Ser33) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02997
Synonyms p-p53 (Ser33), p-p53 (S33), p53 (p-Ser33), p53 (p-S33)

Anti-Phospho-p53 (Ser33) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser33). Anti-Phospho-p53 (Ser33) Polyclonal Antibody can be used in IF,WB.

Anti-Phospho-p53
(Ser33) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-p53 (Ser33) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser33). Anti-Phospho-p53 (Ser33) Polyclonal Antibody can be used in IF,WB.
Synonymsp-p53 (Ser33), p-p53 (S33), p53 (p-Ser33), p53 (p-S33)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from HT29 cells using p53 (Phospho-Ser33) Antibody TMAC-02997 and the same antibody preincubated with blocking peptide.
2. Immunofluorescence staining of methanol-fixed Hela cells using p53 (Phospho-Ser33) Antibody TMAC-02997.
3. Western blot analysis of extracts from HT29 cells, treated with serum or calf intestinal phosphatase (CIP), using p53 (Phospho-Ser33) Antibody TMAC-02997.
verifiedActivityverifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 33 (V-L-S(p)-P-L) derived from Human p53
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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