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Anti-Neuroserpin Antibody (4G149)
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Catalog No. TMAY-01648
Alias Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402
Anti-Neuroserpin Antibody (4G149) is a Mouse antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (4G149) can be used in ELISA,IHC-P.
Anti-Neuroserpin Antibody (4G149)
Anti-Neuroserpin Antibody (4G149)
😃Good
Catalog No. TMAY-01648Alias Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402
Anti-Neuroserpin Antibody (4G149) is a Mouse antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (4G149) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Neuroserpin Antibody (4G149) is a Mouse antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (4G149) can be used in ELISA,IHC-P. |
| Alias | Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4G149 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human SERPINI1 in human brain with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Neuroserpin / SerpinI1 (rh Neuroserpin / SerpinI1; TMPY-01241; NP_005016.1; Met1-Leu410). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Neuroserpin, also known as Protease inhibitor 12 and SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. Neuroserpin is predominantly expressed in the brain, and is expressed in the late stages of neurogenesis during the process of synapse formation. Overexpression of neuroserpin in an anterior pituitary corticotroph cell line results in the extension of neurite-like processes, suggesting that neuroserpin may play a role in cell communication, cell adhesion, and/or cell migration. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. Neuroserpin may also protect neurons from cell damage by tissue-type plasminogen activator. Defects of neuroserpin are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Neuroserpin / SerpinI1 Protein (TMPY-01241) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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