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Anti-EphB1 Antibody (4X729) (Synonyms: Net, Hek6, EPH receptor B1, ENSMUSG00000074119, Elkh, Elk, Cek6, C...)

Name: Anti-EphB1 Antibody (4X729)
Brand: TargetMol
SKU: TMAY-02168
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02168 Copy Product Info

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Anti-EphB1 Antibody (4X729) is a Rabbit antibody targeting EphB1. Anti-EphB1 Antibody (4X729) can be used in ELISA.

Anti-EphB1 Antibody (4X729)

Copy Product Info

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Catalog No. TMAY-02168

Synonyms Net, Hek6, EPH receptor B1, ENSMUSG00000074119, Elkh, Elk, Cek6, C130099E04Rik, AW488255, 9330129L11

Anti-EphB1 Antibody (4X729) is a Rabbit antibody targeting EphB1. Anti-EphB1 Antibody (4X729) can be used in ELISA.

Anti-EphB1 Antibody
(4X729)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$268	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-EphB1 Antibody (4X729) is a Rabbit antibody targeting EphB1. Anti-EphB1 Antibody (4X729) can be used in ELISA.
Synonyms	Net, Hek6, EPH receptor B1, ENSMUSG00000074119, Elkh, Elk, Cek6, C130099E04Rik, AW488255, 9330129L11
Ig Type	Rabbit IgG
Clone	4X729
Reactivity	Human
Specificity	Human EphB1 No cross-reactivity in ELISA with Human EPHB4 Human EPHB6 Mouse EphA1 Mouse EphA4 Mouse EphA6 Mouse EphA7 Mouse EphB3
Application	ELISA
Recommended Dose	ELISA: 1:5000-1:10000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human EphB1 (rh EphB1; TMPY-01997; P54762-1; Met1-Pro540).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Ephrin type-B receptor 1, also known as EphB1, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induces various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. EphB receptor tyrosine kinases are enriched at synapses, suggesting that these receptors play a role in synapse formation or function. We find that EphrinB binding to EphB induces a direct interaction of EphB with NMDA-type glutamate receptors. This interaction occurs at the cell surface and is mediated by the extracellular regions of the two receptors, but does not require the kinase activity of EphB.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human EphB1 protein (TMPY-01997)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

ENSMUSG-00000074119ENSMUSG 00000074119AW-488255AW 488255

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