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BMP-7 Protein, Human, Recombinant

Catalog No. TMPJ-01473
Synonyms: Eptotermin alfa, OP-1, OP1, Osteogenic protein 1, Bone morphogenetic protein 7, BMP7

Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
BMP-7 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg Inquiry $ 310.00
50 μg Inquiry $ 1,165.00
500 μg Inquiry $ 5,832.00
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Biological Description
Technical Params
Product Properties
Description Recombinant Human Bone morphogenetic protein 7 is produced by our Mammalian expression system and the target gene encoding Ser293-His431 is expressed.
Species Human
Expression System Human Cells
Tag Tag Free
Accession Number P18075
Synonyms Eptotermin alfa, OP-1, OP1, Osteogenic protein 1, Bone morphogenetic protein 7, BMP7
Amino Acid Ser293-His431
Construction Recombinant Human Bone morphogenetic protein 7 is produced by our Mammalian expression system and the target gene encoding Ser293-His431 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE.
Molecular Weight 18-23 KDa, reducing conditions
Endotoxin Less than 1 EU/µg as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 5% Mannitol,0.05% Tween80, pH7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.

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Keywords

BMP-7 Protein, Human, Recombinant Eptotermin alfa BMP7Protein,Human,Recombinant OP-1 OP1 Osteogenic protein 1 Bone morphogenetic protein 7 BMP7 recombinant recombinant-proteins proteins protein

 

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