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BRM/BRG1 ATP Inhibitor-1

Name: BRM/BRG1 ATP Inhibitor-1
Brand: TargetMol
SKU: T10616
Price: 179 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10616Cas No. 2270879-17-7

BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s<0.005 μM).

BRM/BRG1 ATP Inhibitor-1

🥰Excellent

Purity: 99.84%

Catalog No. T10616Cas No. 2270879-17-7

Pack Size	Price	Availability
1 mg	$179	In Stock
5 mg	$455	In Stock
10 mg	$683	In Stock
25 mg	$1,180	In Stock
50 mg	$1,730	In Stock
100 mg	$2,430	In Stock
1 mL x 10 mM (in DMSO)	$490	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.84%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s<0.005 μM).
Targets&IC50	BRM/BRG1:﹤0.005 µM

Chemical Properties

Molecular Weight	318.27
Formula	C₁₁H₉F₃N₄O₂S
Cas No.	2270879-17-7
Smiles	OCc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F
Relative Density.	1.659 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (785.50 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (15.71 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1420 mL	15.7099 mL	31.4199 mL	157.0993 mL
5 mM	0.6284 mL	3.1420 mL	6.2840 mL	31.4199 mL
10 mM	0.3142 mL	1.5710 mL	3.1420 mL	15.7099 mL
20 mM	0.1571 mL	0.7855 mL	1.5710 mL	7.8550 mL
50 mM	0.0628 mL	0.3142 mL	0.6284 mL	3.1420 mL
100 mM	0.0314 mL	0.1571 mL	0.3142 mL	1.5710 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc