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TMPD dihydrochloride

Name: TMPD dihydrochloride
Brand: TargetMol
SKU: T40732
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40732Cas No. 637-01-4

TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases.

TMPD dihydrochloride

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Purity: 99.8%

Catalog No. T40732Cas No. 637-01-4

TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.8%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases.
In vitro	TMPD dihydrochloride differentiates organisms that exhibit CYP C oxidase activity and distinguishes between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. TMPD dihydrochloride can be used as a colorimetric indicator[1].

Chemical Properties

Molecular Weight	237.17
Formula	C₁₀H₁₈Cl₂N₂
Cas No.	637-01-4
Smiles	Cl.Cl.CN(C)c1ccc(cc1)N(C)C
Relative Density.	1.1961 g/cm3 (Estimated)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 95 mg/mL (400.56 mM), Sonication is recommended.

DMSO: 13 mg/mL (54.81 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 1 mg/mL (4.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	4.2164 mL	21.0819 mL	42.1638 mL	210.8192 mL
5 mM	0.8433 mL	4.2164 mL	8.4328 mL	42.1638 mL
10 mM	0.4216 mL	2.1082 mL	4.2164 mL	21.0819 mL
20 mM	0.2108 mL	1.0541 mL	2.1082 mL	10.5410 mL
50 mM	0.0843 mL	0.4216 mL	0.8433 mL	4.2164 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0422 mL	0.2108 mL	0.4216 mL	2.1082 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc